Meningioma With Partial and Spontaneous Regression of Peritumoral Edema on Long-Term Follow Up

Abstract

Spontaneous regression of meningioma is rarely observed. We report a one person of an incidentally diagnosed meningioma with a spontaneous regression. The 73-year-old female patient without symptoms showed the right sphenoid meningioma with peritumoral edema. The meningioma was incidentally diagnosed and followed up by MRI for 10 years. The tumor shrank with a decrease of edema on T2 MRI. The initial volume of 58.59 cm<sup>3</sup>, regressed to 37.16 cm<sup>3</sup>.

Case Details

Disease Location

Brain

Personal Characteristics

73-year-old female. She was diagnosed with type 2 diabetes mellitus treated with metformin

Clinical Characteristics

With an incidentally diagnosed meningioma. MRI revealed a large meningioma (47.04×40.18× 62.31 mm) of the right sphenoid

Remission Characteristics

Ten years later, she was admitted due to decreased cognitive function five years ago. MRI showed shrinkage of the meningioma to a size of 42.66×31.72×54.92 mm

Treatment & Mechanisms

Proposed Remission Mechanisms

Calcification of arteries can occur due to old age and dm, followed by a decrease in blood supply in tumor, which leads to a decrease in tumor size.