Spontaneous Remission Of Unidentified Cushing’s Disease Revealed By Hair Cortisol Analysis
van Boven, E., Massolt, E. T., van Rossum, E. F. C., & Kiewiet-Kemper, R. M. (2020). Spontaneous remission of unidentified Cushing's disease revealed by hair cortisol analysis. The Netherlands journal of medicine, 78(5), 297–299.
View Original Source →Case Details
Disease Location
Pituitary gland
Personal Characteristics
31-year-old woman, hypertension, type 2 diabetes mellitus, polycystic ovary syndrome, and hypothyroidism, all diagnosed within a timeframe of three years.
Clinical Characteristics
Admitted with a thunderclap headache. MRI showed pituitary apoplexy in a pituitary macro adenoma. Physical examination was suggestive of cushing’s syndrome. Laboratory testing was consistent with complete anterior hypopituitarism. Hydrocortisone therapy of 80 mg a day was started. Hair cortisol analysis was performed the results showed cyclic but significantly and consistently elevated cortisol levels for the last 22 months. The diagnosis of cushing’s disease in our patient cured by pituitary apoplexy.
Remission Characteristics
Diagnosis of cushing’s disease cured by pituitary apoplexy was established
Treatment & Mechanisms
Proposed Remission Mechanisms
Pituitary apoplexy
Clinical Treatment
Hydrocortisone 80mg/d