Spontaneous Regression Of A Hypoglossal Neurinoma: Case Report And Review Of The Literature.
Santander, X. A., Cotúa, C. E., & Saldaña, C. (2017). spontaneous Regression of a Hypoglossal Neurinoma: Case report and Review of the Literature. World neurosurgery, 105, 1033.e7–1033.e9. https://doi.org/10.1016/j.wneu.2017.06.004
View Original Source →Abstract
BACKGROUND: Hypoglossal neurinomas are very rare intracranial tumors. The management choices include surgery, as the gold standard, and radiosurgery or a combination of both. Little is known about this condition and the behavior of this tumor. CASE DESCRIPTION: A 54-year-old woman presented with a right 12th nerve neurinoma with ipsilateral hemiatrophy of the tongue and spontaneous regression after 1 year of follow-up. CONCLUSIONS: Our case highlights the importance of considering careful observation and diligent follow-up as a treatment option, as these lesions can show spontaneous regression with no invasive approaches.
Case Details
Disease Location
Right hypoglossal schwannoma
Personal Characteristics
54-year-old female
Clinical Characteristics
A 54-year-old woman presented with a 2 year history of pain localized in the right lateral cervical and submandibular region. P/e revealed right hemiatrophy of the tongue and deviation to the contralateral side with no other neurologic signs. MRI revealed a tumor in the right hypoglossal canal with extracranial extension to the posterior side of the internal jugular vein. Based on these clinical and radiologic findings, a nonsurgical diagnosis of hypoglossal schwannoma was made. Further MRI performed for radiotherapy treatment planning purposes showed signs of spontaneous regression of the lesion. The right was halted, and the subsequent MRI at 1 year confirmed a practical remission of the tumor. During this time, the patient did not experience clinical progression but tongue atrophy persisted.
Remission Characteristics
MRI performed for radiotherapy treatment planning purposes showed signs of spontaneous regression of the lesion. The right was halted, and the subsequent MRI at 1 year confirmed a practical remission of the tumor. During this time, the patient did not experience clinical progression but tongue atrophy persisted.
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed