Spontaneous Regression Together With Increased Calcification Of Incidental Meningioma.
Hirota, K., Fujita, T., Akagawa, H., Onda, H., & Kasuya, H. (2014). spontaneous regression together with increased calcification of incidental meningioma. Surgical neurology international, 5, 73. https://doi.org/10.4103/2152-7806.132957
View Original Source →Abstract
BACKGROUND: Regression of meningioma has been reported after hemorrhage or hormonal withdrawal. However, meningioma regression is rarely observed spontaneously. CASE DESCRIPTION: A right falx meningioma was incidentally diagnosed and was followed at every one-year by magnetic resonance imaging (MRI) for over 7 years. The tumor, with a maximum diameter of 4 cm, showed a slightly high density and was enhanced on computed tomography (CT), and a high intensity with a low-intensity core on T2 MRI, with significant edema. The meningioma gradually shrank together with a decrease of edema and increase of calcification. The initial volume, 25.5 cm(3), regressed linearly to less than half, 9.9 cm(3). CONCLUSION: Here, we report a case of an incidentally diagnosed meningioma that regressed spontaneously. The pattern of the regression was similar to that following gamma knife radiosurgery.
Case Details
Disease Location
Right falx meningioma
Personal Characteristics
66-year-old with medical history of HCV, dm2 on insulin.
Clinical Characteristics
Incidentally diagnosed meningioma a right falx meningioma with a maximum diameter of 4 cm showed a slightly high density and was enhanced on CT, and a high intensity with a low-intensity core on t2 MRI, with significant edema. The tumor was followed up with a yearly MRI.
Remission Characteristics
Follow up over 7 years showed complete regression
Treatment & Mechanisms
Proposed Remission Mechanisms
The tumor regression in the present patient may be due to the calcification of tumor cells promoted by a high glucose level.
Non-Clinical Treatment
None reported; insulin for dm2