Cancer Of The Breast Treated Medically

Abstract

A case of spontaneous disappearance of pulmonary metastases of a breast cancer after radical mastectomy is reported. The subsequent reappearance of the initial pulmonary lesion and the later complete regression of that lesion along with many other pulmonary metastases in both lungs after adrenalectomy proved that the lesion was a metastasis of the breast cancer, even though there was no histological diagnosis. The highly hormone-dependent mammary cancer in this patient led me to suggest that the alteration of adrenal cortical activity following a two-stage bilateral radical mastectomy, rather than the host defense factor, was involved in the spontaneous regression of the pulmonary metastases.