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Spontaneous Regression Of A Reye's Tumor: A Case Report

Yang, T. 2023Brain tumor

Yang, T., Wijaya, W. A., & Cao, C. (2023). Spontaneous regression of a Reye's tumor: A case report. Asian journal of surgery, 46(8), 3379–3380. https://doi.org/10.1016/j.asjsur.2023.03.092

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Case Details

Disease Location

Skin

Personal Characteristics

One-year-old boy

Clinical Characteristics

Presented with a spontaneously occurring nodule on the fourth and fifth digits of the right foot, noticed three months earlier, which progressively increased in size. On examination, it is revealed that “kissing lesions” are on the lateral aspect of the fourth digit and the medial aspect of the fifth digit of the right distal and middle phalanx. These nodules are flesh-coloured, confluent, painless, indurated, and ill-circumscribed. A punch biopsy was performed, and the histopathology revealed an elongated, spindle-shaped fibroblast arranged in interdigitating sheets in a collagenous background. Immunohistochemistry (ihc) showed smooth muscle actin (sma+), muscle-specific actin (msa+), and desmin +. The clinical presentation and distinctive histopathological findings confirmed the diagnosis of reye's tumor.

Remission Characteristics

One year later, the tumour regressed spontaneously.

Treatment & Mechanisms

Clinical Treatment

Biopsy