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Complete Spontaneous Remission Of Small Cell Lung Cancer In The Absence Of Specific Treatment: A Case Report

Song, S. H. 2021Lung cancer

Song, S. H., Ha, C. W., Kim, C., & Seong, G. M. (2021). Complete spontaneous remission of small cell lung cancer in the absence of specific treatment: A case report. Thoracic cancer, 12(19), 2611–2613. https://doi.org/10.1111/1759-7714.14124

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Abstract

Small cell lung cancer (SCLC) is a unique tumor that has a distinct clinical behavior and dismal prognosis. If untreated, it can become aggressively malignant, and life expectancy could be limited to weeks. Spontaneous regression of lung cancer has rarely been reported, and among them SCLC is even rarer. The underlying mechanisms of spontaneous regression are poorly understood. Here, we report a case of complete spontaneous SCLC remission in an elderly patient.

Case Details

Disease Location

Lung

Personal Characteristics

80-year-old man. He had smoked 20 cigarettes daily for 50 years.

Clinical Characteristics

Referred with hemoptysis and hoarseness. Chest x-ray revealed a bulging contoured lesion in the left hilum. Chest computed tomography (CT) revealed a malignant tumor in the left upper lobe and enlarged left hilar and mediastinal lymph nodes. Video-assisted thoracoscopic surgery (vats) was performed, and a subaortic lymph node was excised. Pathological examination revealed sclc. He consumed beetroot (beta vulgaris) juice daily for 2 years after sclc was diagnosed.

Remission Characteristics

52 weeks later, chest x-ray revealed the absence of the bulging left hilar contoured lesion. Chest CT scans confirmed complete remission of the previous sclc in the left upper lobe, mediastinum, and hilum

Treatment & Mechanisms

Proposed Remission Mechanisms

Surgical trauma and beetroot intake may play some role in tumor regression

Clinical Treatment

Biopsy, beetroot juice

Non-Clinical Treatment

Beetroot (beta vulgaris) juice