Spontaneous Regression Of Retroperitoneal Metastases From A Primary Pure Anaplastic Seminoma: A Case Report.
Sarid, D. L., Ron, I. G., Avinoach, I., Sperber, F., & Inbar, M. J. (2002). spontaneous regression of retroperitoneal metastases from a primary pure anaplastic seminoma: a case report. American journal of clinical oncology, 25(4), 380–382. https://doi.org/10.1097/00000421-200208000-00012
View Original Source →Abstract
Spontaneous regression of pure seminoma metastases is a rare phenomenon, with only a few cases reported to date. To the best of our knowledge, this is the first report of regression of anaplastic pure seminoma metastases located in the retroperitoneum. We present a 27-year-old man, a marihuana smoker, with metastatic pure anaplastic seminoma in the high retroperitoneal lymph nodes. After orchiectomy, his metastases regressed with no medication. Several mechanisms are suggested to explain this phenomenon, which still remains elusive.
Case Details
Disease Location
Testis
Personal Characteristics
27-year-old man, marijuana smoker
Clinical Characteristics
Severe pain and edema of the left testis that were con- firmed on physical examination. He was diagnosed as having a pure seminoma tumor and underwent left orchiectomy on july 20, 1999. The pathology examina- tion revealed an anaplastic seminoma. Macroscopically, two thirds of the testis had been replaced by gray-yellow tissue; the maximum diameter of the tumor was 6.0 cm and showed extensive areas of necrosis
Remission Characteristics
Computed tomography examination in may 2000 demonstrated complete and spontaneous regression of the tumor
Treatment & Mechanisms
Proposed Remission Mechanisms
Host immunity
Clinical Treatment
Left orchiectomy
Additional Notes
move to male GU