Vanishing Liver Tumours.
Peddu, P., Huang, D., Kane, P. A., Karani, J. B., & Knisely, A. S. (2008). Vanishing liver tumours. Clinical radiology, 63(3), 329–339. https://doi.org/10.1016/j.crad.2007.08.009
View Original Source →Abstract
Spontaneous resolution of liver tumours is a rare, but recognized entity that has been reported to occur within the spectrum of benign and malignant liver tumours occurring in both adult and paediatric population. The aetiology of this unusual phenomenon is not clearly understood. In this article we present case examples of various benign and malignant liver tumours that have regressed spontaneously without treatment together with a review of the literature, and a summary of the current understanding of the pathogenesis of these tumours.
Case Details
Disease Location
Biliary system
Personal Characteristics
54-year-old woman
Clinical Characteristics
Presented with steadily worsening, painless, obstructive jaundice. Clinical laboratory testing found markedly elevated values for serum bilirubin and alkaline phosphatase activity. The patient was investigated with us followed by CT. Both demonstrated a 5 4 cm mass centrally at the confluence of the right and left hepatic ducts with prominent biliary dilatation in both lobes of the liver
Remission Characteristics
Microscopy of a CT-guided biopsy specimen found no evidence of malignancy. Repeat CT-guided biopsy and laparoscopic biopsy followed; histological examination demonstrated infiltration of the liver parenchyma and bile duct wall by mixed inflammatory cells. CT performed 6 months after laparoscopy showed marked regression in the volume of the central hepatic lesion
Treatment & Mechanisms
Proposed Remission Mechanisms
Not discussed
Clinical Treatment
Patient laparoscopy