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Spontaneous Partial Regression Of A Microcystic Jejunal Mesenteric Lymphangioma And A Proposed Management Algorithm

Tan, D. T. M. 2019Other/Unknown

Tan, D. T. M., Chok, A. Y., Farah, B. L., Yan, Y. Y., & Toh, E. L. (2019). Spontaneous partial regression of a microcystic jejunal mesenteric lymphangioma and a proposed management algorithm. BMJ case reports, 12(11), e231037. https://doi.org/10.1136/bcr-2019-231037

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Abstract

Mesenteric lymphangiomas are relatively rare, with clinical symptoms ranging from an asymptomatic presentation to an acute abdomen. The natural history and biological behaviour of this entity can range from slow indolent lesions to aggressive tumours with a risk of malignant transformation. Spontaneous regression of a mesenteric lymphangioma is rare. We herein report a case of a jejunal mesenteric lymphangioma that was initially detected incidentally in an asymptomatic patient with a subsequent sudden increase in size with resulting surrounding mass effect after 9 months and a spontaneous partial regression at surgical resection. Our case is the first reported case which outlines a period in the natural history and evolution of microcystic mesenteric lymphangioma, illustrating the sudden enlargement likely attributable to spontaneous and self-limiting haemorrhage and subsequent partial regression at surgical resection. We thenceforth propose a possible management algorithm for adult patients with mesenteric lymphangiomas.

Case Details

Disease Location

Mesentery

Personal Characteristics

68-year-old chinese male

Clinical Characteristics

Admitted for left hemispheric syndrome secondary to a left middle cerebral artery infarct. During the admission, he developed enterococcus faecalis bacteraemia due to urosepsis. CT scan of the chest, abdomen and pelvis incidentally found a lobulated fluid density lesion in the right flank of the abdomen extending from the subhepatic region along some small bowel loops into part of the mesentery. It was most suspicious for a small bowel mesenteric lymphangioma. 9 months later, CT scan demonstrated an interval increase in size of the mesenteric lesion, which was extending from the right hemipelvis to the central abdomen. There was mass effect causing displacement and mild twisting of the small bowel coupled with encasement of the mesenteric vessels, which resulted in small bowel and mesenteric congestion.

Remission Characteristics

The patient’s symptoms subsided promptly, and his abdomen was soft and non-tender. Intraoperatively, the mesenteric lymphangioma was localised to a 5cm segment of jejunal mesentery and appeared to have partially regressed.

Treatment & Mechanisms

Proposed Remission Mechanisms

Self-limiting haemorrhage is consistent with the spontaneous resolution of the patient’s symptoms and significant size regression on surgical resection.

Clinical Treatment

Surgery

Non-Clinical Treatment

None reported