Spontaneous Remission In Large-vessel Vasculitis: Takayasu Arteritis And Paraneoplastic Disorder Associated With Thymic Carcinoma
Onishi, A., Tanaka, Y., & Morinobu, A. (2019). Spontaneous remission in large-vessel vasculitis: Takayasu arteritis and paraneoplastic disorder associated with thymic carcinoma. Scandinavian journal of rheumatology, 48(1), 79–81. https://doi.org/10.1080/03009742.2018.1469165
View Original Source →Abstract
Large-vessel vasculitis (LVV) affects the aorta and its major branches, and has two major variants: Takayasu arteritis (TAK) and giant cell arteritis (GCA). TAK is a chronic disease treated with gl...
Case Details
Disease Location
Arteries
Personal Characteristics
64-year-old man
Clinical Characteristics
Presented with weight loss. Laboratory analyses revealed elevated c-reactive protein (crp) and anaemia of chronic disease. CT showed a thymic tumour without vascular abnormalities. Fdg-PET/CT revealed high-grade uptake in the thymic mass and intermediate-grade uptake in the carotid, subclavian, and thoracic arteries and the abdominal aorta. Large-vessel vasculitis (lvv) with high-grade thymoma was suspected. Two years later, the mass had enlarged and surgical resection was performed. Pathological findings revealed basaloid carcinoma.
Remission Characteristics
At the time of surgery, crp and vascular uptake on PET had normalized
Treatment & Mechanisms
Proposed Remission Mechanisms
Lvv may resolve spontaneously in some patients with tak or neoplasm
Clinical Treatment
Biopsy
Non-Clinical Treatment
None reported