Spontaneous Remission Of Infant Acute Myeloid Leukemia With A Novel Four-way Translocation
Kubo, N., Iwabuchi, H., Imamura, M., Saitoh, A., & Imai, C. (2020). Spontaneous remission of infant acute myeloid leukemia with a novel four-way translocation. Pediatric blood & cancer, 67(2), e28052. https://doi.org/10.1002/pbc.28052
View Original Source →Case Details
Disease Location
Skin, bone marrow
Personal Characteristics
Female born at 35 weeks of gestation
Clinical Characteristics
The patient was referred at 36 days of age with papules over her forehead and trunk. Physical examination revealed an infant with multiple, elevated reddish brown papules. Bone marrow smear prepared from a very small amount of obtained material showed leukemic cells. A skin biopsy also showed infiltration of leukemic cells. A diagnosis of acute myeloid leukemia (aml; fab m5b) was made. Fish analysis identified three signals of kat6a in 95.1% of cells
Remission Characteristics
The skin nodules regressed spontaneously. She attained complete remission at around 90 days
Treatment & Mechanisms
Proposed Remission Mechanisms
None reported
Clinical Treatment
Skin biopsy, bone marrow aspiration
Non-Clinical Treatment
None reported