Spontaneous Remission Of Diffuse Large B Cell Lymphoma In The Stomach And The Continuation Of Remission For 10 Years
Sugiyama, T., Arita, K., Shinno, E., & Nakajima, T. (2018). Spontaneous Remission of Diffuse Large B Cell Lymphoma in the Stomach and the Continuation of Remission for 10 Years. Case reports in gastroenterology, 12(3), 699–703. https://doi.org/10.1159/000494750
View Original Source →Abstract
According to the literature, spontaneous remission of aggressive lymphomas is extremely rare; gastric non-Hodgkin lymphomas, such as mucosa-associated lymphoid tissue lymphomas, often regress due to Helicobacter pylori treatment or no progression, even in a watch-and-wait strategy. Although spontaneous remission of diffuse large B cell lymphomas in the stomach was very rarely reported, the follow-up periods of the cases of spontaneous remission are within 2 years and most cases are likely to relapse after the first remission. Here, we report that a diffuse large B cell lymphoma in the stomach showed spontaneous remission within 2 months after the initial diagnosis and the remission is still continuing for 10 years without any specific treatments against this aggressive lymphoma.
Case Details
Disease Location
Stomach
Personal Characteristics
62-year-old woman
Clinical Characteristics
Upper gastroduodenal endoscopy showed an elevated tumor with a diameter of 4 cm at the gastric body. The pathologic diagnosis was a diffuse large b cell non-hodgkin lymphoma being CD20 and cd79a positive. H. Pylori infection was positive and the histology showed intestinal metaplasia as well as gastric atrophy
Remission Characteristics
2 months later, abdominal CT and pulmonary CT were normal. Gastroduodenal endoscopy was retested, but the tumor in the stomach was not detected anymore.
Treatment & Mechanisms
Clinical Treatment
Biopsy h. Pylori eradication therapy
Non-Clinical Treatment
None reported