Spontaneous Regression Of Malignant Lymphoma Of The Maxillary Gingiva Following Biopsy
Aoki, Y., Hasegawa, S., Miyabe, S., & Nagao, T. (2022). Spontaneous regression of malignant lymphoma of the maxillary gingiva following biopsy. International journal of oral and maxillofacial surgery, 51(9), 1145–1148. https://doi.org/10.1016/j.ijom.2021.09.006
View Original Source →Abstract
A case of spontaneous regression of malignant lymphoma of the maxillary gingiva following a biopsy is reported. An 84-year-old man was referred to the hospital with chief complaints of swelling of the anterior maxillary gingiva. A non-tender swelling with an ulcer was observed. There was no abnormal bone resorption in the anterior maxillary region and no swelling of the cervical lymph nodes. A biopsy was performed, and the patient was diagnosed with diffuse large B-cell lymphoma. The lesion regressed spontaneously 3 weeks after the initial biopsy. Two years have passed since the spontaneous regression and no recurrence has been observed. If malignant lymphoma regresses on biopsy, observation is considered to be sufficient.
Case Details
Disease Location
Gingiva
Personal Characteristics
84-year-old man, history of gastric cancer status post gastrectomy and prostate cancer treated with bicalutamide
Clinical Characteristics
Painless swelling in the anterior maxillary gingiva. He discontinued bicalutamide 2 weeks prior. Intraoral examination revealed a non-tender swelling of the la- bial gingiva over the right maxillary central and lateral incisors that was 20 x 17 mm in size, round, soft, and ulcerated. A biopsy confirmed the diagnosis of diffuse large b-cell lymphoma (dlbc)
Remission Characteristics
18 fdg PET CT showed no uptake by the primary or other sites. Therefore, the primary site was re-biopsied, but the results showed gingivitis
Treatment & Mechanisms
Proposed Remission Mechanisms
Discontinuation of bicalumatide
Clinical Treatment
Biopsy
Non-Clinical Treatment
None reported