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About the Project

Spontaneous Regression Of Hepatocellular Carcinoma: Three Case Reports And A Categorized Review Of The Literature.

Oquinena, S. 2009Liver cancer

Oquiñena, S., Iñarrairaegui, M., Vila, J. J., Alegre, F., Zozaya, J. M., & Sangro, B. (2009). spontaneous regression of hepatocellular carcinoma: three case reports and a categorized review of the literature. Digestive diseases and sciences, 54(5), 1147–1153. https://doi.org/10.1007/s10620-008-0447-z

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Case Details

Disease Location

Liver

Personal Characteristics

4-year-old male had a diagnosis of hepatitis b virus- related liver cirrhosis with complete portal vein thrombosis in 1989.

Clinical Characteristics

In february 1998 CT revealed no focal lesions but after intra-arterial lipiodol injection a 15-mm lesion in segment vi was detected. This lesion progressively grew thereafter to reach 30 mm in september 1998. In march 1999, arterial blood flow was observed by doppler ultrasonography (us) inside the portal thrombus adjacent to this ill-defined lesion. Serum AFP at that time was elevated.

Remission Characteristics

No lesion was detected on CT performed on may 2000 when AFP was slightly elevated.

Treatment & Mechanisms

Proposed Remission Mechanisms

Disturbance in hepatic circulation associated with portal vein thrombosis

Additional Notes

recurrence