A Case Of Spontaneous Remission Of Non-hodgkin's Lymphoma In The Lung
Li, S., Yu, F. H., & Yanfen, S. (2025). A Case of Spontaneous Remission of Non-Hodgkin's Lymphoma in the Lung. Clinical case reports, 13(3), e70265. https://doi.org/10.1002/ccr3.70265
View Original Source →Abstract
A 72-year-old male with a lung lesion was diagnosed with non-Hodgkin's lymphoma through percutaneous needle lung biopsy. The patient's lung tumor disappeared during follow-up 4 months later without any standard antitumor treatments. This is a rare case of spontaneous tumor remission.
Case Details
Disease Location
Lung
Personal Characteristics
72-year-old male, abnormal CEA and ca19-9 levels for 7 years, 3 year history of copd and idiopathic pulmonary fibrosis
Clinical Characteristics
PET-CT scan revealed increased metabolic activity in a mixed ground glass density nodule in the right lower lobe. Conservative management with traditional chinese medicine (tcm) was chosen. Oral pirfenidone was started and later changed to nintedanib. CT-guided percutaneous lung lesion biopsy was performed revealing non-hodgkin's lymphoma derived from b cells.
Remission Characteristics
5 months after the biopsy a CT showed that the tumor had disappeared
Treatment & Mechanisms
Proposed Remission Mechanisms
Biopsy procedures disrupt the tumor microenvironment and may also induce sr
Clinical Treatment
Pirfenidone, nintedanib
Non-Clinical Treatment
Traditional chinese medicine