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Portal Vein Aneurysm With Complete Spontaneous Regression After 10 Years Using Conservative Treatment

Watanabe, Y. 2020Other/Unknown

Watanabe, Y., Takase, K., Okada, K., Aikawa, M., Okamoto, K., & Koyama, I. (2020). Portal vein aneurysm with complete spontaneous regression after 10 years using conservative treatment. Clinical journal of gastroenterology, 13(5), 940–945. https://doi.org/10.1007/s12328-020-01131-6

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Abstract

Portal vein aneurysms are rare vascular findings for which there are no optimal treatment guidelines. The scarce knowledge about their etiology, natural history, and management mean that there are limited treatment options. Here, we describe the case of a 69-year-old woman who presented with a 35-mm hypoechoic area in the hilar region of the liver that was accidentally detected by ultrasonography. Color Doppler ultrasonography demonstrated a mass with internal flow contiguous with portal vein, which was confirmed to be a portal vein aneurysm by computed tomography. Given that she experienced no symptoms of impending rupture or thrombosed aneurysms, we adopted a conservative treatment. Follow-up imaging demonstrated slow progression of the aneurysm diameter, from 35 to 43 mm at 3 years, and to 48 mm at 6 years; subsequent imaging after 6 years did not show any change in the diameter from 48 mm. However, the portal vein aneurysm completely regressed with no complications at a follow-up of over 10 years. This case suggests that long-term observation with periodic imaging may be an acceptable therapeutic option for asymptomatic portal vein aneurysms that show no short-term improvement. This case report contributes to a better understanding of how to treat this rare disease.

Case Details

Disease Location

Portal vein

Personal Characteristics

69-year-old woman

Clinical Characteristics

She was diagnosed with a liver tumor by a medical examination. An abdominal ultrasonography revealed a 35 mm × 32 mm cystic mass in the hilar region, which showed color flow on doppler ultrasonography. CT showed a mass that was more clearly visible during the portal venous phase, consistent with a portal vein aneurysm. Follow-up cts demonstrated slow progression of the pva diameter from 35 to 43 mm at 3 years, and to 48 mm at 6 years. The pva was stable in size on annual imaging after the 6-year follow-up; it was 48 mm at 7, 8, and 9 years

Remission Characteristics

Ten years after the original diagnosis, surveillance imaging revealed that her pva had undergone complete spontaneous regression; there was a thrombus in part of the left portal vein, but the portal vein flow in the liver was adequately maintained

Treatment & Mechanisms

Proposed Remission Mechanisms

None reported

Clinical Treatment

None reported

Non-Clinical Treatment

None reported