Spontaneous Regression Of A Large Nasal Hemangioma In A 55-year-old Male
Lee J. H. (2022). Spontaneous Regression of a Large Nasal Hemangioma in a 55-Year-Old Male. Ear, nose, & throat journal, 101(6), NP235–NP237. https://doi.org/10.1177/0145561320963695
View Original Source →Abstract
Lobular capillary hemangiomas (LCHs) are benign vascular lesions of the skin, oral cavity, and, rarely, the nasal cavity that are histologically characterized by capillary proliferation and a lobular architecture. The etiology of LCH is not well understood, but the possible underlying factors include trauma, hormonal influences, and angiogenic growth factors. This case report describes the spontaneous complete regression of an LCH without further surgery although it was incompletely excised. To our knowledge, this is a rare case for a middle-aged man.
Case Details
Disease Location
Nose
Personal Characteristics
55-year-old male
Clinical Characteristics
He was referred with a left nasal mass. He complained of left nasal obstruction and frequent nasal bleeding that had progressed over 6 months. Nasal endoscopy revealed a large reddish mass filling the left anterior nasal cavity. CT scan of the sinus revealed a dense soft tissue measuring 33 x 21 x 20 mm, which extended along the left inferior turbinate without bony destruction. Using a pinpoint tip bovie and a suction coagulator, the mass was excised at its origin from the medial and inferior surfaces of the inferior turbinate with nasal endoscopy guidance. Significant bleeding occurred during the removal. Surgery was discontinued and nasal packing was performed. Histopathological examination confirmed the diagnosis of a lobular capillary hemangioma (lch). A nasal splint tube was inserted into his left nasal cavity to relieve his nasal obstruction
Remission Characteristics
No residual mass was observed during the examination of his left nasal cavity by nasal endoscopy 2 years after surgery, and his follow-up CT showed complete resolution.
Treatment & Mechanisms
Proposed Remission Mechanisms
Vascular endothelial growth factors (vegas) rapidly decrease after delivery; a lack of vegf is associated with apoptosis of endothelial cells, which leads to the regression of hemangiomas
Clinical Treatment
Partial excision
Non-Clinical Treatment
None reported