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Delayed Iatrogenic Direct Carotid Cavernous Fistula Following Flow Diversion For Aneurysm With Spontaneous Healing: A Case Report

Voura, E. B. 2024Other/Unknown

Voura, E. B., Stulb, J. R., Eller, J. L., Padalino, D. J., & Ramaswamy, R. (2024). Delayed Iatrogenic Direct Carotid Cavernous Fistula Following Flow Diversion for Aneurysm With Spontaneous Healing: A Case Report. Cureus, 16(4), e58944. https://doi.org/10.7759/cureus.58944

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Abstract

An abnormal connection between the carotid artery and cavernous sinus is referred to as a carotid cavernous fistula (CCF). A direct CCF results when the connection occurs between the intracranial internal carotid artery (ICA) and the cavernous sinus. These events are typically the result of a head injury, but can also be iatrogenic, resulting from various intracranial procedures. Direct CCF occurrences rarely heal spontaneously due to the high flow rate across the fistula. In this report, we present an uncommon case involving a delayed iatrogenic direct CCF, which developed following the placement of a pipeline flow-diverting stent that was used to treat a cerebral aneurysm. Interestingly, this unusual iatrogenic direct CCF subsequently spontaneously resolved within a few months. To our knowledge, this is the only case of a delayed CCF occurring with the use of a flow-diverting sent, which then resolved on its own. This report recounts our experience with the case.

Case Details

Disease Location

Internal carotid artery

Personal Characteristics

56-year-old female, smoker

Clinical Characteristics

Referred with dizziness. Cerebral angiogram confirmed a left paraophthalmic ica aneurysm measuring 3.6 mm. Angiography completed several weeks later confirmed that the aneurysm had expanded - measuring 5x4.9 mm - and that it also had some dysmorphic attributes. She underwent pipeline embolization for the ica aneurysm. During the preparation for her six-month follow-up visit and angiogram, she mentioned hearing a “swishing sound” in her left ear. It revealed a direct ccf arising at the proximal end of the stent with venous drainage into both cavernous sinuses and posterior drainage into the inferior petrosal sinuses on both sides.

Remission Characteristics

Cerebral angiography nine months later showed complete spontaneous resolution of ccf.

Treatment & Mechanisms

Proposed Remission Mechanisms

Pipeline embolization

Clinical Treatment

None reported

Non-Clinical Treatment

None reported