Spontaneous Regression Of A Low-grade Renal Cell Carcinoma With Oncocytic Features After Renal Mass Biopsy
Srivastava, A., Meyer, A. R., Pierorazio, P. M., Rowe, S. P., Allaf, M. E., & Gorin, M. A. (2018). Spontaneous Regression of a Low-Grade Renal Cell Carcinoma With Oncocytic Features After Renal Mass Biopsy. Clinical genitourinary cancer, 16(6), e1083–e1085. https://doi.org/10.1016/j.clgc.2018.07.012
View Original Source →Case Details
Disease Location
Kidney
Personal Characteristics
66-year-old woman. History of recurrent urinary tract infections, arthritis, hypertension, and migraines
Clinical Characteristics
Was incidentally found to have a small left-sided renal mass on non-contrast magnetic resonance imaging performed for assessment of new-onset back pain. CT demonstrated an enhancing left-sided anteromedial renal mass measuring 2.3 x 1.7 cm. Renal mass biopsy with CT guidance revealed a low-grade renal cell carcinoma (rcc) with oncocytic features. The patient underwent an uncomplicated robot-assisted laparoscopic partial nephrectomy.
Remission Characteristics
Surgical pathology revealed lymphohistiocytic inflammation without evidence of viable tumor cells. Additionally, eosinophilic ghost cells without nuclei were observed, suggestive of spontaneous tumor regression
Treatment & Mechanisms
Proposed Remission Mechanisms
The release of tumor antigens may have contributed to the regression of the mass.
Clinical Treatment
Biopsy, partial nephrectomy