Spontaneous Regression Of Solid-pseudopapillary Neoplasms With Hepatic Metastases
Li, X., & Liu, Y. (2022). Spontaneous regression of solid-pseudopapillary neoplasms with hepatic metastases. Hepatobiliary surgery and nutrition, 11(1), 169–170. https://doi.org/10.21037/hbsn-21-438
View Original Source →Case Details
Disease Location
Liver
Personal Characteristics
42-year-old female
Clinical Characteristics
Presented due to abdominal distension for 3 weeks. MRI scan showed a huge mass (16 cm diameter) in the pancreatic tail and irregular low-density shadows (0.4–5.6 cm diameter) in the liver, with left outer lobe atrophy. The patient underwent distal pancreatectomy, splenectomy, left lateral hepatectomy, and pathological examination confirmed the diagnosis of solid-pseudopapillary neoplasms. The remaining liver metastases were not treated post-operation.
Remission Characteristics
At 20 months follow-up, enhanced CT of the abdomen showed shrinkage and disappearance of the liver metastases
Treatment & Mechanisms
Proposed Remission Mechanisms
Spontaneous regression of the hepatic metastases may be attributed to primary tumor resection tipping the immune-mediated balance towards the host, enabling or stimulating the immune system to control residual disease
Clinical Treatment
Distal pancreatectomy, splenectomy, left lateral hepatectomy,