Spontaneous Necrosis And Regression Of Focal Nodular Hyperplasia
Nguyen, T. T. L., Le Bail, B., & Frulio, N. (2024). Spontaneous necrosis and regression of focal nodular hyperplasia. Diagnostic and interventional imaging, 105(12), 507–508. https://doi.org/10.1016/j.diii.2024.07.009
View Original Source →Case Details
Disease Location
Liver
Personal Characteristics
39-year-old woman
Clinical Characteristics
Underwent liver ultrasound examination to investigate abnormalities in liver function tests, which revealed multiple liver lesions. The patient was taking a progestogen-only oral contraceptive (desogestrel). An initial MRI confirmed at least four liver lesions. Two lesions, one in the left lobe and one in segment viii, had a typical focal nodular hyperplasia (fnh) pattern. Another lesion in segment vii was suggestive of fnh, and another small lesion in segment vi was more atypical of fnh.
Remission Characteristics
One year later, follow-up MRI revealed morphologic changes of the lesion in segment vii consistent with a neurotically remodeled lesion
Treatment & Mechanisms
Proposed Remission Mechanisms
Vascular changes, possibly due to arterial thrombosis, may facilitate intralesional ischemic necrosis and lead to regression of fnh.
Clinical Treatment
Desogestrel