Spontaneous Regression Of A Malignant Primary Bone Tumour
Inger Dissinc, Jan Heerfordt, Torben Schiødt & Otto Sneppen (1978) spontaneous Regression of a Malignant Primary Bone Tumour, Acta Orighthopaedica Scandinavica, 49:1, 49-53, DOI: 10.3109/17453677809005723
View Original Source →Abstract
A histologically confirmed malignant, primary bone tumour in the pelvis, presumably an osteosarcoma, underwent spontaneous regression. The large tumour was inoperable and gave rise to severe pain as well as difficulty in walking. After 2 years of progression, with increasing desition improved spontaneously, and at present the patient is alive, almost symptom-free, after 6 years follow-up.
Case Details
Disease Location
Pelvis
Personal Characteristics
36-year-old male
Clinical Characteristics
Radiography disclosed widespread osteolytic lesion in left half of pelvis open biopsy at anterior demarcation of tumor in iliac bone exploratory operation through wide posterior approach tumor in iliac bone measuring 12x8x8 cm histological examination of tumor tissue displayed tumor was inoperable condition deteriorated steadily--> radiologic examination displayed destruction of left half of pelvis
Remission Characteristics
In course of latter half of 1973, reveral occurred pain subsided, normal walking resumed, tumor area increasingly delimited & sclerosed
Treatment & Mechanisms
Proposed Remission Mechanisms
Possible causes: hypersensitivity reaction hemorrhage in tumor reaction to tumor protein immunological factors
Clinical Treatment
Symptomatic treatment (non-weight-bearing & analgesic medication)