Regression Of Cerebral Post-transplantation Lymphoma Under Cyclosporin A Reduction
Fric, M., HARTmann, A., Klehr, H. U., Pfeifer, U., & Herberhold, C. (1990). Regression zerebraler Posttransplantationslymphome unter Cyclosporin-A-Reduktion [Regression of cerebral post-transplantation lymphoma under cyclosporin A reduction]. Klinische Wochenschrift, 68(23), 1189–1194. https://doi.org/10.1007/BF01815278
View Original Source →Abstract
4.5 months after successful kidney transplantation a Non-Hodgkin-lymphoma with polymorph centroblastic appearance of the tonsillar gland developed in a 21 years old male patient during immunosuppressive therapy with cyclosporine A and prednisone parallel to infection with Epstein Barr virus. Focal epileptic seizures occurred and were due to cerebral posttransplantation lymphomas as proven by brain biopsy. Reduction of immunosuppressive therapy led to complete remission as shown by CCT and MRI.
Case Details
Disease Location
Cerebral post-transplantation lymphoma
Personal Characteristics
21- year-old male
Clinical Characteristics
Kidney transplant non-hodgkin lymphoma with polymorph centroblastic appearance of tonsillar gland developed (4 mths after transplant) focal epilepatientic seizures occurred due to cerebral posttransplantation lymphomas (proven by brain biopsy)
Remission Characteristics
Reduction of immunosuppressive therapy induced complete remission verified by cct & MRI
Treatment & Mechanisms
Clinical Treatment
Immunosuppressive therapy with cyclosporine a & prednisone parallel to infection with epstein barr virus