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Spontaneous Regression Of Pulmonary Metastases From Breast Angiosarcoma

Kim, S. 2008Sarcoma

Kim, S. W., Wylie, J., spontaneous Regression of pulmonary Metastases from Breast Angiosarcoma, Sarcoma, 2008, 940656, 4 pages, 2008. https://doi.org/10.1155/2008/940656

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Abstract

Spontaneous regression of cancer is a rare phenomenon. We present a rare case of pulmonary metastases in a 72-year-old woman with metastatic breast angiosarcoma. She was diagnosed with a breast angiosarcoma in 2005 and underwent a total mastectomy and postoperative radiotherapy. Unfortunately, a year later she was found to have multiple lung and scalp metastases but in a view of her poor general fitness, she was not a candidate for chemotherapy and was kept on regular followup. Despite the absence of any treatment, the followup chest X-ray showed a significant reduction in the number and size of lung nodules and her scalp lesions regressed completely. Seven months after the diagnosis of metastatic disease, the nodules in her scalp remain controlled.

Case Details

Disease Location

Ulcerating lesion in left breast

Personal Characteristics

72-year-old female

Clinical Characteristics

True-cut biopsy of mass confirmed angiosarcoma CT scan showed multiple bilateral lung nodules (breast angiosarcoma metastasized to the lungs) physical examination revealed subcutaneous nodules on scalp

Remission Characteristics

Scalp nodules regressed in one year subcutaneous scalp nodules no longer palpable reduction in number and size of lung nodules

Treatment & Mechanisms

Proposed Remission Mechanisms

Mechanism is unknown

Clinical Treatment

Left simple mastectomy postoperative radiotherapy delivered to chest wall via single 8 mev electron field (40 gy in 15 fractions over 3 weeks) electron boost to scar of 10 gy in 4 fractions