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Carcinoma Of The Larynx A Case Of Apparent Regression After Inadequate Therapy

Levine et al., 1970Other/Unknown

Levine MI, Reidbord HE, Busis SN. Carcinoma of the Larynx: A Case of Apparent Regression After Inadequate Therapy. Arch Otolaryngol. 1970;91(4):385–386. doi:10.1001/archotol.1970.00770040543017

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Abstract

Regression of carcinoma of the larynx after inadequate therapy is rare. Carcinoma of the larynx was diagnosed histologically in one patient following a stripping procedure of the larynx. This was not considered adequate therapy, but further therapy was refused. There was no evidence of this tumor at laryngoscopy two years later or at autopsy 12 years after the initial tumor was found. This patient developed another unusual finding, a metachronous carcinoma of the lung, which caused his death.

Case Details

Disease Location

Larynx

Personal Characteristics

62-year-old male 2 packs cigarettes weekly

Clinical Characteristics

Complained of cough & exertional dyspnea chest roentgenogram showed changes consistent with pneumoconiosis (1954) in 1955, complained of hoarseness of 6 weels' duration laryngeal mass found on right true vocal cord (carcinoma of larynx)

Remission Characteristics

Patient next followed-up in 1957 due to postnasal drainage laryngoscopy revealed no abnormality developed metachronous carcinoma of lung, which caused death no evidence of laryngeal cancer at autopsy 12 years after initial tumor found

Treatment & Mechanisms

Clinical Treatment

Symptomatic therapy prescribed for pneumoconiosis laryngoscopy showed papillomatous, polypoid mass on right vocal cord, involved ventral surface of cord--> lesion stripped as well as possible patient refused total laryngoscopy