Spontaneous Regression Of Malignant Disease: Report Of Three Cases
Margolis, J., & West, D. (1967). spontaneous regression of malignant disease: report of three cases. Journal of the American Geriatrics Society, 15(3), 251–253. https://doi.org/10.1111/j.1532-5415.1967.tb01134.x
View Original Source →Case Details
Disease Location
Kidneys
Personal Characteristics
43-year-old white male
Clinical Characteristics
Admitted may 1956 due to gradual development of partial hemiplegia with motor & sensory components physical exam showed mild, chronic, choked disc with partial right hemiplegia--> arteriograms indicated a large tumor biopsy specimen was diagnosed as astrocytoma (grade iii)
Remission Characteristics
More than 9 years post diagnosis of astrocytoma, patient died following bouts of acute & chronic infection of kidneys at autopsy, multiple abscesses of kidneys present, but no evidence of astrocytoma found
Treatment & Mechanisms
Proposed Remission Mechanisms
Fever and/or infection may be related regression (patient had several bouts of acute & chronic kidney infection)
Clinical Treatment
Operation revealed tumor with large cyst--> cyst drained & 150 ml fluid removed given large doses of sedatives & narcotics, needed frequent treatment for overdosages of narcotics & barbiturates