Spontaneous Regression Of Squamous Cell Lung Carcinoma With Adrenal Metastasis
Sperduto, P., Vaezy, A., Bridgman, A., & Wilkie, L. (1988). spontaneous regression of squamous cell lung carcinoma with adrenal metastasis. Chest, 94(4), 887–889. https://doi.org/10.1378/chest.94.4.887
View Original Source →Abstract
A 61-year-old man was found to have squamous cell carcinoma of the left hilum with metastasis to the left adrenal gland documented by needle aspiration. About two years later, the primary tumor is not detectable, and the adrenal gland is of normal size on follow-up computerized tomography. To our knowledge, this is the first documented case of spontaneous regression of squamous cell carcinoma of the lung with adrenal metastasis.
Case Details
Disease Location
Left hilum
Personal Characteristics
61-year-old white male smoked >1 pack of cigarettes/day for all adult life anxiety & depression with auditory hallucinations (received amitriptyline & perphenazine daily)moderate chronic obstructive pulmonary disease with chronic productive cough & excision of multiple basal cell skin carcinomas
Clinical Characteristics
Routine chest x-ray film on admission for left flank pain revealed left hilar mass CT of chest & upper abdomen revealed 3 cm mass in posterior left hilum & 6 cm left adrenal mass needle biopsy of left hilar mass revealed squamous cell carcinoma CT guided needle aspiration of left adrenal gland revealed metastatic squamous cell carcinoma no treatment undertaken
Remission Characteristics
Since discharge, patient remained asymptomatic followed up ever 3 mths stopped smoking & continued previous medications (amitripatientyline & perphenazine) follow-up chest x-ray films displayed gradual decrease in size of left hilar mass left hilum was normal at last x-ray film CT scan of upper abdomen revealed a left adrenal gland of normal size
Treatment & Mechanisms
Clinical Treatment
Left anterior thoracotomy for diagnostic biopsy