Spontaneous Regression Of Pulmonary Metastatic Melanoma
Ong, S. F., Harden, M., Irandoust, S., & Lee, R. W. (2015). spontaneous regression of pulmonary metastatic melanoma. Respirology case reports, 4(1), 7–9. https://doi.org/10.1002/rcr2.138
Abstract
Our case represents the seventh case of complete spontaneous regression of melanoma metastatic to the lung, and the only case with histologic confirmation of both the primary and pulmonary metastatic lesions. The patient was pregnant twice between the time of her initial diagnosis of primary melanoma and pulmonary metastatic disease.
Case Details
Disease Location
Mets left upper lobe lung
Personal Characteristics
83 -year-old male
Clinical Characteristics
Incidental 15 mm left upper lobe lingula segment lung nodule as part of the investigation of peripheral neuropathy. Computed-tomography-guided biopsy demonstrated malignant melanoma. Serial PET/CT scans were performed at 3 and 6 months as part of the treatment planning workup, which confirmed no progression of disease, but the left upper lobe nodule suv had reduced to 0.9 at 6 months
Remission Characteristics
Decraesing lad 3/6 months. Vats lul nodule 8 mo after dx, no evidence of active cancer. Just necrotic cells.
Treatment & Mechanisms
Proposed Remission Mechanisms
None proposed
Clinical Treatment
Biopsy (after initial regression) wedge resection of the left upper lobe lesion