Case Series Of Duodenal Follicular Lymphoma, Observed By Magnified Endoscopy With Narrow-band Imaging
Norimura, D., Isomoto, H., Imaizumi, Y., Akazawa, Y., Matsushima, K., Inoue, N., Yamaguchi, N., Ohnita, K., Shikuwa, S., Arima, T., Hayashi, T., Takeshima, F., Miyazaki, Y., & Nakao, K. (2011). Case series of duodenal follicular lymphoma, observed by magnified endoscopy with narrow-band imaging. Gastrointestinal endoscopy, 74(2), 428–434. https://doi.org/10.1016/j.gie.2011.03.1237
View Original Source →Case Details
Disease Location
Duodenal follicular
Personal Characteristics
67 -year-old female
Clinical Characteristics
Underwent upper gi endoscopy to investigate epigastric and back pain. She had mild anemia. At duodenoscopy, small whitish granules were observed in the second portion of the duodenum. Magnified chromoendoscopy with crystal violet showed dilatation and irregularity of the villous structures. Magnified endoscopy with nvi demonstrated coil and elongated microvascular patterns within the surface of the lesions and opaque white spots under the microvessels histopathologic exam of target biopsy specimens revealed the presence of the follicular structures consisting of abnormal lymphoid cells with dense nuclei immunohistochemical analysis revealed that the neoplastic cells were positive for CD10 and 20 but negative for CD2 and cyclin d1. Bcl-2 protein was expressed in the cytoplasm of most neoplastic cells diagnosis of duodenal follicular lymphoma. Wait-and-see was adopted.
Remission Characteristics
Repeat duodenoscopy 3 months later revealed the multiple white lesions were improved and had almost disappeared 7 months later nbi-magnified endoscopy were substantially recovered and histological specimens from the mucosa showed no neoplastic changes
Treatment & Mechanisms
Proposed Remission Mechanisms
No major mechanism proposed
Clinical Treatment
None reported
Non-Clinical Treatment
None reported