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Spontaneous Regression Of A Recurrent Hepatocellular Carcinoma.

Gomez & Anz, 1998Liver cancer

Gómez Sanz, R., Moreno Gonzalez, E., Colina Ruiz-Delgado, F., Garcia-Muñoz, H., Ochando Cerdan, F., & Gonzalez-Pinto, I. (1998). spontaneous regression of a recurrent hepatocellular carcinoma. Digestive diseases and sciences, 43(2), 323–328. https://doi.org/10.1023/a:1018802321581

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Case Details

Disease Location

Liver with multiple metastases

Personal Characteristics

66-year-old man, chronic hepatitis c virus and chronic gastritis, no history of alcohol consumption or blood transfusions

Clinical Characteristics

5- months history of pain in the right upper quadrant, normal pe. Ultrasonography disclosed a large (10-cm), solid, well-defined mass in the right liver lobe. CT confirmed the presence of the lesion. Microscopic study of fnab specimen confirmed the diagnosis of well-differentiated hcc. Laboratory tests showed positive HCV. The patient underwent surgical treatment. One year after surgery, the patient was readmitted with intense abdominal pain and painful masses at the level of both sternoclavicular joints. CT disclosed an undetermined number of intraabdominal masses (prerenal, retrogastric) suggesting recurrence of hcc. Fnab of the sternoclavicular lesions revealed the presence of hcc metastasis.

Remission Characteristics

The patient began to improve clinically and recover his appetite. The sternoclavicular lesions gradually disappeared and the abdominal pain remitted. Disappearance of the intraabdominal (confirmed by CT) and cutaneous masses in the sternoclavicular region 16 months after resection of the hcc

Treatment & Mechanisms

Proposed Remission Mechanisms

Possible immune mechanism

Clinical Treatment

Surgical treatment catheter-delivered morphine chloride, ketorolacotrometamole, amitripatientyline and levomepromazine s-adenosyl l-methionine