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Spontaneous Remission Of B-cell Chronic Lymphocytic Leukemia Associated With T Lymphocytic Hyperplasia In Bone Marrow

Morris, 2003Leukemia

Morris D. J. (2003). spontaneous remission of B-cell chronic lymphocytic leukemia associated with T lymphocytic hyperplasia in bone marrow. Southern medical journal, 96(3), 324. https://doi.org/10.1097/01.SMJ.0000061507.81880.04

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Case Details

Disease Location

Bone marrowithblood

Personal Characteristics

74 -year-old female

Clinical Characteristics

In september 1996, patient presented with wbc count of 23,300/ul with 57% lymphocytes marrow biopsy was hypercellular, showing cll with diffuse and nodular involvement of lymphoid cells, including peritrabecular collections flow cytometry revealed an abnormal b-cell population coexpressing the CD5 t-cell marker and strongly expressing the kappa light chain CD5/CD9 coexpression was 54% findings suggested cll but patient was not treated for cll patient's lymphocyte and wbc counts remained elevated until feb 2002

Remission Characteristics

Feb 2002, wbc was normal with 46% lymphocytes and 55% neutrophils in june 2002, wbc remained normal with normal absolute lymphocyte count patient appeared to be in complete clinical remission

Treatment & Mechanisms

Clinical Treatment

None reported

Non-Clinical Treatment

None reported