Spontaneous Regression Of Metastatic Extraskeletal Myxoid Chondrosarcoma
Kinoshita, T., Kamiyama, I., Hayashi, Y., Asakura, K., Ohtsuka, T., Kohno, M., Emoto, K., Nakayama, R., Morioka, H., & Asamura, H. (2015). spontaneous Regression of Metastatic Extraskeletal Myxoid Chondrosarcoma. The Annals of thoracic surgery, 100(4), 1465–1467. https://doi.org/10.1016/j.athoracsur.2014.12.107
View Original Source →Abstract
Spontaneous regression of tumors is very unusual and is defined as a partial or complete disappearance of metastatic tumors without any treatment. This phenomenon has been reported in almost all types of cancer. The patient was a 25-year-old woman who presented with multiple pulmonary nodules on her bilateral lungs on the annual chest roentgenograph. Simultaneously, a swelling mass on her subcutaneous inguinal region was observed. The diagnosis of the inguinal mass was extraskeletal myxoid chondrosarcoma. The inguinal mass and pulmonary nodules spontaneously regressed without any treatment after biopsy. The patient was doing well without evidence of recurrence at 1 year after the operation without any additional therapy. Our case is the first clinical one that indicated a possibility of histologic regression of extraskeletal myxoid chondrosarcoma.
Case Details
Disease Location
Lung
Personal Characteristics
25-year-old woman
Clinical Characteristics
Presented with multiple pulmonary nodules on her bilateral lungs on the annual chest x-ray. Simultaneously, a swelling mass on her subcutaneous inguinal region was observed. The diagnosis of the inguinal mass was emc. The inguinal mass and pulmonary nodules spontaneously regressed without any treatment after biopsy, except for one lesion located on her right lower lobe, which regrew. Right lower lobectomy was performed. The pathologic diagnosis was confirmed as pulmonary metastasis of emc
Remission Characteristics
The inguinal mass and pulmonary nodules spontaneously regressed without any treatment after biopsy
Treatment & Mechanisms
Proposed Remission Mechanisms
Surgical biopsy triggered an immune response
Clinical Treatment
Biopsy right lower lobectomy