Spontaneous Regression Of Primary Malignant Lymphoma Of The Prostate
monthszen, Y., Nakahara, M., & Nishisaka, T. (2013). spontaneous regression of primary malignant lymphoma of the prostate. Case reports in urology, 2013, 363072. https://doi.org/10.1155/2013/363072
View Original Source →Abstract
We herein report a case of primary lymphoma of the prostate, which arose in an 85-year-old male with dysuria. CT and MRI examinations demonstrated a large mass in the prostate. A transrectal ultrasound-guided biopsy of the prostate was performed. The histological examination showed diffuse large B-cell lymphoma. The large lesion in the prostate showed spontaneous regression. Spontaneous regression of primary lymphoma of the prostate has not been reported previously. The spontaneous regression of primary lymphoma of the prostate observed in this patient suggests that observation may represent a viable treatment option following a biopsy that has provided a histopathological diagnosis.
Case Details
Disease Location
Prostate
Personal Characteristics
85 -year-old male was diagnosed with prostatic hypertrophy in 2003
Clinical Characteristics
Referred in november 2009 for dysuria his serum prostate-specific antigen level was 3.4ng/ml. He underwent treatment for prostate hyperplasia, but the dysuria worsened contrast enhanced CT demonstrated a large heterogeneous mass involving the prostate, boundary of the bladder, and the left ureter. There was also hydronephrosis, hydroureter, and two enlarged lymph nodes in the pelvis the tumor was hypointense and shown to have originated from the left peripheral zone of the prostate on t2 MRI. The tumor infiltrated the seminal vesicles, rectum, and bladder. I.e. The imaging studies revealed a large pelvic mass originating from the prostate, sarcoma-like tumor was suggested prostate biopsy identified dlbcl, histological exam of hematoxylin and eosin sections showed the infiltration of polygonal atypical cells, which were ihc positive for CD20 and lca the patient refused chemo and radiotherapy
Remission Characteristics
Precontrast CT demonstrated a diminution of the size of the lymphoma after the prostate biopsy, the two enlarged lymph nodes in the pelvis disappeared and both the left hydronephrosis and the hydroureter improved there has been no local recurrence or distant metastasis in the 31 month since the biopsy
Treatment & Mechanisms
Proposed Remission Mechanisms
Probably attributable to immunological response by the host that arises as a result of the injury due to an infection with bacteria or viruses or the injury caused by the biopsy of the prostate the etiology of sr in this case is likely a result from biopsy
Clinical Treatment
None reported
Non-Clinical Treatment
None reported