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Spontaneous Remission Of Congenital Acute Myeloid Leukemia With Skin Involvement And T(1;11)(p32;q23)

Jesudas et al., 2017Leukemia

Jesudas, R., Buck, S. A., & Savasan, S. (2017). spontaneous remission of congenital acute myeloid leukemia with skin involvement and t(1;11)(p32;q23). Pediatric blood & cancer, 64(3), 10.1002/pbc.26269. https://doi.org/10.1002/pbc.26269

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Case Details

Disease Location

Skin/bone marrow

Personal Characteristics

2- months-old female

Clinical Characteristics

Skin lesions first seen at 1- months of age. Pe showed fading skin lesions skin biopsy revealed CD4/CD56-positive and myeloperoxidase-negative infiltrating monotonous cells with irregular folded and indented nuclei. Bone marrow morphology and flow cytometry findings were consistent with acute myeloid leukemia positron emission tomography did not indicate extramedullary site involvement

Remission Characteristics

She achieved remission by morphology, cytogenetic, and flow cytometric studies in 6 weeks

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed