Primary Cutaneous Cd4+ Small/medium-sized T-cell Lymphoma With Spontaneous Regression After Biopsy
González Fernández, D., Valdés Pineda, F., Gómez Díez, S., & Vivanco Allende, B. (2015). Primary Cutaneous CD4+ Small/Medium-Sized T-Cell Lymphoma With spontaneous Regression After Biopsy. Actas dermo-sifiliograficas, 106(9), 767–768. https://doi.org/10.1016/j.ad.2015.02.015
View Original Source →Case Details
Disease Location
Left nasal ala
Personal Characteristics
44 -year-old male no past history of interest
Clinical Characteristics
Primary cutaneous CD4+ small/medium sized t-cell lymphoma originally seen for a nodular lesion that had appeared on the left nasal ala 3 weeks earlier and had grown progressively at consultation, the nodular lesion was 2.5cm in diameter. There were no other lesions and no palpable ln or organomegaly incisional biopsy revealed a dense, diffuse lymphocytic infiltrate in the dermis. The lymphocyte population was formed of small-sized lymphocytes associated with another population of medium-sized lymphocytes, both showing pleomorphism epidermotropism was minimal and there was slight infiltration of follicular epithelium ihc revealed a lymphocyte population formed predominately of t cells that expressed CD3 and 5. The CD4/8 ratio was greater than 2. T-cell receptor rearrangement revealed a monoclonal t-cell population blood tests and CT was normal. A diagnosis of pcsm-tcl was made
Remission Characteristics
10 days after the biopsy, the lesion was seen to regress and it had completely disappeared after 3 months after a year, the patient remained asymptomatic and no new lesions had appeared
Treatment & Mechanisms
Proposed Remission Mechanisms
No major mechanism reported
Clinical Treatment
None reported
Non-Clinical Treatment
None reported