Burkitt's Lymphoma: Remissions Following Seemingly Non-specific Therapy
David, J., & Burkitt, D. (1968). Burkitt's lymphoma: remissions following seemingly non-specific therapy. British medical journal, 4(5626), 288–289. https://doi.org/10.1136/bmj.4.5626.288
View Original Source →Abstract
Long-term remissions observed in four out of eight unselected patients with Burkitt's lymphoma following seemingly non-specific treatment with Septicemine, are described. This is regarded as strong evidence of an effective immunological response.
Case Details
Disease Location
Left maxilla, left orbit
Personal Characteristics
15 -year-old male
Clinical Characteristics
Admitted with a tumor of the upper part of the left maxilla involving the orbit attempatients at biopsy failed to secure tumor tissue, but the clinical features and progression of growth precluded any diagnosis other than a malignant neoplasm clinical and radiological appearances strongly suggested a diagnosis of burkitt's tumor septicemine was given, but the tumor growth continued for 2 months the tumor was not histologically confirmed
Remission Characteristics
A sudden change then occurred with rapid and complete remission 3 years later, he remained well
Treatment & Mechanisms
Proposed Remission Mechanisms
Either the treatment or an immunological mechanism host response to cytotoxic therapy an immunological response to tumor trauma, i.e. Tumor-antibody formation host defense mechanisms
Clinical Treatment
Septicemine
Non-Clinical Treatment
None reported