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Spontaneous Remission Of A Squamous Cell Carcinoma Of The Floor Of The Mouth

Deandrade et al., 2014Squamous cell carcinoma (skin)

de Andrade Sousa, A., Lopes Rena, R., Souza Silva, G., Marcos Arantes Soares, J., Porcaro-Salles, J. M., Nunes, L., Alves Mesquita, R., & Jham, B. C. (2014). spontaneous remission of a squamous cell carcinoma of the floor of the mouth. Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 42(7), 1536–1539. https://doi.org/10.1016/j.jcms.2014.04.026

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Abstract

Spontaneous remission is a rare, but well recognized event in oncology. Certain tumours, such as melanomas, hypernephromas and neuroblastomas, are known for showing spontaneous regression. Similarly, spontaneous regression of oral lymphomas, as well as oropharyngeal and recurrent tongue carcinomas, has been reported. Here, we present a novel case of a patient with a primary squamous cell carcinoma on the floor of the mouth whose tumour regressed spontaneously in three months, without any treatment. We also review of the literature on the spontaneous remission of oral cancer and discuss possible mechanisms for this phenomenon.

Case Details

Disease Location

Oral cavity, floor mouth

Personal Characteristics

62 -year-old male, etoh/tob hx

Clinical Characteristics

Squamous cell carcimomna (+) biopsy

Remission Characteristics

Cr at 3 months follow up

Treatment & Mechanisms