Burkitt's Lymphoma: Remissions Following Seemingly Non-specific Therapy
David, J., & Burkitt, D. (1968). Burkitt's lymphoma: remissions following seemingly non-specific therapy. British medical journal, 4(5626), 288–289. https://doi.org/10.1136/bmj.4.5626.288
View Original Source →Abstract
Long-term remissions observed in four out of eight unselected patients with Burkitt's lymphoma following seemingly non-specific treatment with Septicemine, are described. This is regarded as strong evidence of an effective immunological response.
Case Details
Disease Location
Right maxilla, left orbit, intracranial
Personal Characteristics
9 -year-old male
Clinical Characteristics
Admitted with a large lymphoma of the right maxilla invading the orbit the dagnosis was confirmed histologically there was also evidence of intracranial involvement and his general condition was very poor the tumor was partially removed surgically and treatment with septicemine was begun after improvement, intracranial complications cause the childs death a months later
Remission Characteristics
After 2 months of treatment, the tumor mass remaining from the surgery had shrunk considerably in size, and histology showed massive tumor necrosis, though apparently viable tumor cells were also present his general condition had greatly improved
Treatment & Mechanisms
Proposed Remission Mechanisms
Either the treatment or an immunological mechanism host response to cytotoxic therapy an immunological response to tumor trauma, i.e. Tumor-antibody formation host defense mechanisms
Clinical Treatment
Septicemine
Non-Clinical Treatment
None reported