Burkitt's Lymphoma: Remissions Following Seemingly Non-specific Therapy
David, J., & Burkitt, D. (1968). Burkitt's lymphoma: remissions following seemingly non-specific therapy. British medical journal, 4(5626), 288–289. https://doi.org/10.1136/bmj.4.5626.288
View Original Source →Abstract
Long-term remissions observed in four out of eight unselected patients with Burkitt's lymphoma following seemingly non-specific treatment with Septicemine, are described. This is regarded as strong evidence of an effective immunological response.
Case Details
Disease Location
Left maxilla
Personal Characteristics
11 -year-old male
Clinical Characteristics
In 1961, he was admitted with a tumor invading the left side of the nose which was histologically diagnosed as a lymphoma or reticulosarcoma the swelling of the palate and orbital involvement characteristic of burightkitt's lymphoma subsequently developed the tumor enlarged rapidly and the child was discharged as inoperable eventually the child was administered septicemine
Remission Characteristics
After one month's treatment, the tumor began to regress and a months later the boy returned to school he was seen one year later with no clinical evidence of tumor and he was well 7 years later
Treatment & Mechanisms
Proposed Remission Mechanisms
Either the treatment or an immunological mechanism host response to cytotoxic therapy an immunological response to tumor trauma, i.e. Tumor-antibody formation host defense mechanisms
Clinical Treatment
Septicemine
Non-Clinical Treatment
None reported