Spontaneous Regression Of Acquired Immune Deficiency Syndrome-related, High-grade, Extranodalnon-hodgkin’s Lymphoma
Karnad, A. B., Jaffar, A., & Lands, R. H. (1992). spontaneous regression of acquired immune deficiency syndrome-related, high-grade, extranodal non-Hodgkin's lymphoma. Cancer, 69(7), 1856–1857. https://doi.org/10.1002/1097-0142(19920401)69:7<1856::aid-cncr2820690730>3.0.co;2-q
View Original Source →Case Details
Disease Location
Forehead, right costochondral junction, left nasolabial fold
Personal Characteristics
30 -year-old male homosexual history of pneumocystis carinii pneumonia (pcp), mycobacterium avium-intracellulare bacteremia, and oral candidiasis
Clinical Characteristics
Presented with fever and chills of 2 weeks duration, he also had a chest wall mass that caused no pain a firm, nontender mass measuring 3x3cm was present on the forehead, and a 4x4 cm tender mass was overlying the right costochondral junction results of a chest roentgenogram showed a left upper lobe infiltrate results of a wedge biopsy of the chest wall mass showed diffuse large cell lymphoma with numerous mitotic figures the patient received pentamidine via IV for presumed recurrent pcp 21 days after admission, a new mass measuring 2x2 was found, it grew rapidly in the left nasolabial fold. This was excised the excision biopsy showed diffuse large cell nhl the patient remained ill with recurrent pneumonia he died 4 weeks after the nhl diagnosis
Remission Characteristics
8 days after admission, his forehead and chest wall tumors were smaller 12 days after his admission, they complete regressed at time of death there was still no evidence of recurrence in the forehead or chest wall
Treatment & Mechanisms
Proposed Remission Mechanisms
Concomitant viral or bacterial infections mediating sr, the role of host immunity, particularly antitumor t-cell responses and the role of interferons
Clinical Treatment
IV pentamidine excisional biopsy
Non-Clinical Treatment
None reported