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About the Project

Spontaneous Remission Of Hepatocellular Carcinoma After Massive Gastrointestinal Haemorrhage

Tocci, G. 1990Liver cancer

Tocci, G., Conte, A., Guarascio, P., & Visco, G. (1990). spontaneous remission of hepatocellular carcinoma after massive gastrointestinal haemorrhage. BMJ (Clinical research ed.), 300(6725), 641–642. https://doi.org/10.1136/bmj.300.6725.641

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Case Details

Disease Location

Liver

Personal Characteristics

79 year old man, active liver cirrhosis (non-hav, non-hnv), he used prednisone + azathiopine for 3 months. All treatment was stopped in march.

Clinical Characteristics

Routine laboratories showed increased levels of tumour markers. Us and CT of the liver showed a round dense image, 5 cm in diameter with a necrotic core near the hepatic hilum. A biopsy was taken and the diagnosis of micotrabecular hepatocarcinoma was made. In the following months, he devolved jaundice and tumour marker serum concentration increased. 4 months after diagnosis his general condition deteriorated. An IV hydrocorightison therapy was started, complicated with hematemesis and shock. He required blood transfusion.

Remission Characteristics

5 months later a us should tumour size reduciton. A CT/us control after 1 month showed further reduction. 3 years later the tumour disappeared.

Treatment & Mechanisms

Proposed Remission Mechanisms

Severe hemorrhagic shock related