Protracted Benet From Paradoxical Kinesia In Typical And Atypical Parkinsonisms
Bonanni, L., Thomas, A., Anzellotti, F., monthsaco, D., Ciccocioppo, F., Varanese, S., Bifolchetti, S., D'Amico, M. C., Di Iorio, A., & Onofrj, M. (2010). Protracted benefit from paradoxical kinesia in typical and atypical parkinsonisms. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 31(6), 751–756. https://doi.org/10.1007/s10072-010-0403-5
View Original Source →Case Details
Disease Location
Basal ganglia
Personal Characteristics
58 -year-old male retired truck driver, family history of ipd.
Clinical Characteristics
Left arm resting tremor and rigidity was cause for ipd diagnosis which followed for 5 years. Tremor was unresponsive to l-dopa and anticholinergic treatments, while rigidity was partly resolved, rbd was recorded. Updrs score was 24 (4 points for left arm tremor), freezing was a score of 3, fog-q was 16. Mmse was 16. Self-reported difficulties turning in bed and walking to the bathroom at nighttime.
Remission Characteristics
2 months after quake, tremor in left hand was a 2 in updrs motor scale, freezing was a 1, fog-q was 4. In the 3rd months after the quake the tremor reappeared with a score of 4, updrs was 22, freezing was 3, and fog-q was 16
Treatment & Mechanisms
Proposed Remission Mechanisms
Noradrenergic augmentation (effect of a life threatening event)/different noradrenergic responses to stress compensatory activation of cerebellar circuitry activation of basal ganglia reserves pk may occur in patients with core and supportive elements typical of ipd-d or dlb
Clinical Treatment
L-dopa 400mg/day,
Non-Clinical Treatment
Earthquake (life-threatening event)