Spontaneous Complete Regression Of Hepatic Epithelioid Haemangioendothelioma.
Otrock, Z. K., Al-Kutoubi, A., Kattar, M. M., Zaatari, G., & Soweid, A. (2006). spontaneous complete regression of hepatic epithelioid haemangioendothelioma. The Lancet. Oncology, 7(5), 439–441. https://doi.org/10.1016/S1470-2045(06)70697-0
View Original Source →Case Details
Disease Location
Liver with lung mets
Personal Characteristics
75-year-old woman. No history of hepatitis, blood transfusions, or alcohol intake. Her family history was negative for malignant disease, and she was not taking any prescribed drugs.
Clinical Characteristics
Presented with a 3- months history of upper abdominal pain associated with distention and change in bowel habits associated with fatigue and weight loss of 5 kg in the preceding 4 months. P/e: the patient was pale, but not icteric; vital signs were within normal limits. She had mild tenderness in the right upper quadrant of the abdomen without hepatosplenomegaly. Laboratory results were within normal range. CT showed multiple suspicious lesions in the liver and a few lesions in the lung bases. Biopsy of the liver lesions was done. The tumour was initially diagnosed as a poorly differentiated carcinoma
Remission Characteristics
20 months later, after an improvement in her clinical condition and a weight gain of more than 10 kg, a repeat CT showed resolution of all hepatic lesions. Pathological material was reassessed and immuno-staining was done and concluded with the diagnosis of epithelioid haemangioendothelioma. Without any type of treatment, the patient improved and gained weight, follow-up CT showed complete regression of the liver lesions with faint bibasal pulmonary lesions remaining.