spontaneous healing of large femoral corightical bone defects: does genetic predisposition play a role?

Case Details

Disease Location

Case 1: right femur

Personal Characteristics

Case 1: 26-year old male motorcyclist

Clinical Characteristics

Fractures in multiple locations due to motorcycle accident; bone defect in femur measured 15cm; bone transporight to femur delayed to due to infection in upper limb and other surgeries

Remission Characteristics

New bone formation in femur noted and surgery was deferred; 6 months after injury patient was able to fully bear weight without any pain and radiographs showed that callus had bridged the long bone defect; confirmed filling 9 months after surgery

Treatment & Mechanisms

Proposed Remission Mechanisms

For all cases, genetic predisposition; more complex fracture patterns may heal faster; bone growth may be supported by intramedullary devices and thorough wound debridation

Clinical Treatment

Case 1: wound debridement and application of external fixator to the femoral fracture; retrograde femoral nail to femoral fracture; surgical treatment of other fractures

Non-Clinical Treatment

For all cases, none reported stated