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Spontaneous Remission Of Nephrotic Syndrome In A Patient With Diabetic Nephropathy And Parkinson's Disease

Heras et al., 2011Other/Unknown

Heras, M., Sáiz, A., Fernández-Reyes, M. J., Sánchez, R., Molina, A., Rodríguez, M. A., & Alvarez-Ude, F. (2011). spontaneous remission of nephrotic syndrome in a patient with diabetic nephropathy and Parkinson's disease. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 31(3), 368–369. https://doi.org/10.3265/Nefrologia.pre2011.Feb.10784

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Case Details

Disease Location

Kidney

Personal Characteristics

74-year-old male, history of dm, double coronary bypass, dvt, pe, prostate adenoma, hiatus hernia and chronic renal failure. Biopsy showed nodular glomerulosclerosis with a morphological substrate of diabetic nephropathy

Clinical Characteristics

Presented with anasarca, weight gain and decrease in the frequency of diuresis. A week before he had developed very itchy petechiae on his arm and the back of his hands.

Remission Characteristics

Subsequent outpatient follow-up showed analytical changes and the patient has not presented new episodes of fluid retention.

Treatment & Mechanisms

Proposed Remission Mechanisms

He had developed cutaneous lesions on his upper limbs. This process could have been triggered by an immune mechanism, leading to an increase in glomerular permeability and, subsequently, severe with spontaneous remission some months later

Clinical Treatment

For parkinson's: carbidopa/entacapone/levodopa, ropiniroleand rasagiline for fluid retention: diuretics, irbesartan, atenolol, statins andoral anticoagulants