A searchable database of
medically documented cases

About the Project

Rare Spontaneous Remission Of Hepatic Artery Aneurysm Following Abo Incompatible Living Donor Liver Transplantation: A Case Report

Ushigome et al., 2007Liver cancer

Ushigome, H., Koshino, K., Sakai, K., Suzuki, T., Nobori, S., Matsuyama, M., Okajima, H., Okamoto, M., & Yoshimura, N. (2011). Rare spontaneous remission of hepatic artery aneurysm following ABO incompatible living donor liver transplantation: a case report. Transplantation proceedings, 43(6), 2424–2427. https://doi.org/10.1016/j.transproceed.2011.05.036

View Original Source →

Abstract

A 60-year-old male patient with an unknown cause for cirrhosis and a hepatoma underwent an ABO incompatible living donor liver transplantation (LDLT) from his son. The transplanted graft was his son's right lobe. For ABO incompatible transplantation, splenectomy was performed for desensitization. A catheter was inserted into the recipient's right hepatic artery for subsequent local immunosuppression. On the 15th postoperative day, a fusiform 15 × 10 mm aneurysm was observed in the graft right hepatic artery using ultrasonography and hepatic arteriography. At that time, the patient was also diagnosed to have an intraperitoneal abscess at the bottom of his left diaphragm. Administering antibiotics, we tried to embolize the aneurysm because of fear of rupture, but this manever failed because it was difficult to insert the wire in to the aneurysm to produce a stenosis around its proximal neck. However, because the aneurysm was not detectable on the 37th postoperative day, it was assumed to have embolized spontaneously. This relatively rare case revealed a hepatic artery aneurysm that spontaneously regressed after ABO incompatible LDLT.

Case Details

Disease Location

Liver

Personal Characteristics

60 years old male patient, cirrhosis secondary to idiopathic hepatitis

Clinical Characteristics

Patient underwent abo incompatible living donor liver transplantation for end-stage liver disease secondary to cirrhosis and hepatoma due to an unidentified hepatitis. Posterior development of a fusiform 15 x10 mm aneurysm in the graft right hepatic artery at the hepatic artery anastomosis.

Remission Characteristics

The aneurysm began to contract after the 34th postoperative day. Then, was not detectable on the 37th postoperative day. It was assumed to have embolized spontaneously.

Treatment & Mechanisms

Proposed Remission Mechanisms

Slow blood flow through the aneurysm

Clinical Treatment

Splectomy and inserightion of catheter into recipient's right hepatic artery. Prostanglandin, methylprednisolone and heparin continuously injected. Antibiotics treatment after discover of aneurysm.