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Spontaneous Regression Of Langerhans Cell Histiocytosis In A Neonate With Multiple Bony Lesions

Mcelligott et al., 2008Other/Unknown

McElligott, J., McMichael, A., Sangüeza, O. P., Anthony, E., Rose, D., & McLean, T. W. (2008). spontaneous regression of langerhans cell histiocytosis in a neonate with multiple bony lesions. Journal of pediatric hematology/oncology, 30(1), 85–86. https://doi.org/10.1097/MPH.0b013e31815cc3d7

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Abstract

We report the case of a newborn with Langerhans cell histiocytosis involving the skin and multiple bones. All lesions resolved without therapy. This case underscores the benefits of a conservative approach in the absence of risk organ involvement.

Case Details

Disease Location

Blood

Personal Characteristics

Newborn delivered by cesarean section.

Clinical Characteristics

Langerhans cell histiocytosis involving the skin and multiple bones.

Remission Characteristics

1 moth-follow up showed improvement, some lesions dissapeared completely. At age of 4 months, she remained asymptomatic and growing normally. At 6 years old she is healthy and no clinical evidence of the disease.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

No treatment, just follow-up