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Hemolytic Non-uremic Syndrome

Chen et al., 2012Other/Unknown

Chen, K. S., Neuneright, C. E., Crary, S. E., & Buchanan, G. R. (2012). Hemolytic non-uremic syndrome. Pediatric blood & cancer, 59(1), 167–169. https://doi.org/10.1002/pbc.23264

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Abstract

We describe three children who developed isolated but severe microangiopathic hemolytic anemia without other manifestations of hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP). All three recovered without specific treatment. We propose that they represent a unique phenotype in the spectrum of TTP and HUS, which we term "hemolytic non-uremic syndrome."

Case Details

Disease Location

Blood

Personal Characteristics

3 years old male

Clinical Characteristics

Bloody diarrhea, low hemoglobin level

Remission Characteristics

Two weeks after treatment, hemoglobin levels increased.

Treatment & Mechanisms

Proposed Remission Mechanisms

Not discussed

Clinical Treatment

(1) hydration and blood transfussion with packed blood cells.