Spontaneous Remission After A Year Of Romiplostim In An Adult Patient With Refractory Primary Immune Thrombocytopenia
Perera, M., Suarez, A., Luzardo, H., Lopez, J., & Molero, T. (2012). spontaneous remission after a year of romiplostim in an adult patient with refractory primary immune thrombocytopenia. Annals of hematology, 91(9), 1497–1498. https://doi.org/10.1007/s00277-012-1437-y
View Original Source →Case Details
Disease Location
Spleen
Personal Characteristics
Male patient aged 58 years old with history of hypertension, dyslipidemia, type ii diabetes and two previous m-year-oldcardial infarctions with stent implantation.
Clinical Characteristics
Patient admitted with skin hemorrhages, petechiae and oral mucosa bleeding. Chest pain with stent stenosis. Diagnosis of primary immune thrombocytopenia (itp).
Remission Characteristics
Four months after 1 year of treatment, the patient maintained stable platelet count.
Treatment & Mechanisms
Proposed Remission Mechanisms
Pharmacological treatment with romiplostim as a cause of sr, as previous cases reported.
Clinical Treatment
Corticosteroid therapy (oral prednisone). Rescue therapy with gammaglobulins. Romiplostim.